Whitman Chambers. The Campanile Murders. (1933) 315,  pp.
Bill Bartlett, police reporter for the Times-Star, gets personally involved in a murder investigation after an argument with his would-be girlfriend, Lillian Voyne, a college student/roadhouse singer. After dropping her off on campus so that she can keep an appointment with Malcolm Jannings, one of her classmates who is the chimes-ringer in the Campanile—the clock tower at the center of the campus—Bill decides to wait around for her. The music stops suddenly and a shot rings out from the top of the tower. The police arrive and Bill accompanies them to the top, where they find Jannings shot in the head...and the killer mysteriously vanished. Not trusting the police to solve the crime, Bill enlists the aid of Dr. C. Edson Hawley, a popular chemistry professor at the University and a noted criminologist who has succeeded where the police had failed in the past. Lillian is soon identified as the prime suspect—by both the police and Dr. Hawley—and Bill makes it his mission to prove them all wrong.
Although (in typical Chambers style) the names Berkeley and California are never mentioned, and the university is called State University, it is clear that the actions takes place on and around the University of California. The description of the Campanile matches Sather Tower exactly, and references to other Berkeley landmarks like the Greek Theater and College Avenue, in addition to San Quentin and the ferryboat system, make it pretty obvious that the setting is Berkeley.
Setting: University of California, Berkeley (State University)